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The Journey of the drug molecules in the body

The Journey of the drug molecules in the body Random walk of the molecules and its path!!! It can be easily imagined that the drug molecules are in random movement through out the body। It is carried mainly by blood and only fraction of administered drug is likely to interact with the target sites to evoke a pharmacological response leading to therapeutic effect. Drug reaching its target is like US marines haunting a wanted terrorist in a dessert!!!Human body is machine having its own design to suite its need for input of oxygen and food, and supply of these to each and every cell of the body. The cells in the process of making energy are likely to churn out waste products like carbon dioxide, urea, ketone bodies, uric acid etc., These waste products should be thorn out of the human body as these can cause harmful effects if gets accumulated in the system. The human body has its own systematic control over input and output system.The human body can be viewed as magic box with several c...

General Principles Of Pharmacology

In general terms, pharmacology is the science of drug action on biological systems. In its entirety, pharmacology embraces knowledge of the sources, chemical properties, and biological effects and therapeutic uses of drugs. It is a science that is basic not only to medicine, but also to pharmacy, nursing, dentistry and veterinary medicine. Pharmacology over years has integrated with other medical and basic sciences like physiology, biochemistry, and pathology that it is very difficult to draw lines among them. Pharmacological studies range from those that examine the effects of chemical agents on sub cellular mechanisms, to those that deal with the potential hazards of pesticides and herbicides, to those that focus on the treatment and prevention of major diseases with drug therapy. Pharmacologists also use molecular modeling and computerized design as drug discovery tools to understand cell function. New pharmacological areas include the genomic and proteomics approaches for therapeut...

General Principles Of Pharmacology

In general terms, pharmacology is the science of drug action on biological systems. In its entirety, pharmacology embraces knowledge of the sources, chemical properties, and biological effects and therapeutic uses of drugs. It is a science that is basic not only to medicine, but also to pharmacy, nursing, dentistry and veterinary medicine. Pharmacology over years has integrated with other medical and basic sciences like physiology, biochemistry, and pathology that it is very difficult to draw lines among them. Pharmacological studies range from those that examine the effects of chemical agents on sub cellular mechanisms, to those that deal with the potential hazards of pesticides and herbicides, to those that focus on the treatment and prevention of major diseases with drug therapy. Pharmacologists also use molecular modeling and computerized design as drug discovery tools to understand cell function. New pharmacological areas include the genomic and proteomics approaches for therapeut...

Pharmacology

Pharmacology (from Greek φάρμακον, pharmakon, "drug"; and -λογία, -logia) is the study of drug action.[1] More specifically it is the study of the interactions that occur between a living organism and exogenous chemicals that alter normal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities. Pharmacology is not synonymous with pharmacy, which is the name used for a profession, though in common usage the two terms are confused at times. Pharmacology deals with how drugs interact within biological systems to affect function. It is the study of drugs, of the body's reaction to drugs, the sources of drugs, their nature, and their properties. In contrast, pharmacy is a medical science concerned with the safe and effective use of medicines. The origins of clinical pharmacology date back ...