Nalufin dose and effects

Nalufin Nalufin ampules image

Composition: Each ampoule 1ml contains: Nalbuphine Hydrochloride 20mg

Properties: -    Nalufin® (Nalbuphine Hydrochloride) is a synthetic narcotic agonist-antagonist analgesic of the phenanthrene series. -    Nalufin® (Nalbuphine Hydrochloride) is a potent analgesic. Its analgesic potency is essentially equivalent to that of morphine on a milligram basis. -    The onset of action of Nalufin® (Nalbuphine Hydrochloride) occurs within 2-3 minutes after intravenous administration, and in less than 15 minutes following subcutaneous or intramuscular injection. The plasma half-life of Nalbuphine is 5 hours, and the duration of analgesic activity has been reported to range from 3 to 6 hours.

Indications: -    Relief of moderate to severe pain, including that associated with myocardial infarction, cancer,    orthopedic problems and renal or biliary colic. -    As a supplement of balanced anesthesia. -    Pre-operative and post-operative analgesia. -    Obstetrical analgesia during labor and delivery.

Contra-Indictions: Known hypersensitivity to Nalbuphine.

Adverse Effects:-   Most frequent: Sedation -    Less frequent: Sweating, nausea, vomiting, dizziness, vertigo, dry mouth & headache. -    Other adverse effects which occurred (incidence 1% or less): •    C.N.S.: Nervousness, depression, restlessness, floating feeling, confusion, faintness, hallucination, euphoria, dysphoria and numbness. •    Cardiovascular: Hypertension, hypotension, bradycardia and tachycardia. •    Respiratory: Respiratory depression, dyspnea and asthma. •    Gastrointestinal: Cramps, dyspepsia and bitter taste. •    Dermatological: Itching and urticaria.

Dosage & Administration: -    The usual recommended adult dose is 10-20mg for 70kg individual administered subcutaneously, intramuscularly or intravenously. -    This dose may be repeated every 3-6 hours as necessary. -    In non-tolerant individuals, the recommended single maximum dose is 20mg, with a maximum total daily dose of 160 mg. -    Pre-medication by subcutaneous, intramuscular or intravenous injection of 0.1- 0.2mg /kg. -    Induction by intravenous injection of 0.3-1.0mg/kg over 10-15 minutes. -    Intra-operative analgesia by intravenous injection of 0.25-0.5mg/kg at 30 minutes intervals. -    Myocardial infarction: By slow intravenous injection of 10-20 mg repeated after 30 minutes if necessary. -    In patients who have been chronically receiving morphine, codeine, or other opiate agonists with similar duration of action, 25% of the usual dose of nalbuphine HCl is given initially. The patient is observed for withdrawal symptoms (abdominal cramps, nausea, vomiting, lacrimation, rhinorrhea and anxiety). -    If these symptoms are troublesome, morphine may be given I.V. slowly in small increments until withdrawal symptoms are relieved. If withdrawal symptoms do not occur, Nalbuphine doses may be increased progressively until the desired level of analgesia is obtained.

How supplied: Nalufin® is a sterile solution available in ampoules 1ml containing 20mg Nalbuphine Hydrochloride in packs of 1 or 5 ampoules. Myodonia tablets- ميودونيا أقراص - الهيستامين لمزودى الرعاية الصحية - اضرار حبوب منع التدخين champix -Varenicline (Champix) for smoking cessation - nitrofurination side effects اخطر المشاكل الموجودة New Liquid Colchicine Dosage Form -

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